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446 : ADAMTS13 Expressed In Platelets Offers Systemic Protection Against Arterial Thrombosis and Therapeutic Benefits In Murine Models Of Thrombotic Thrombocytopenic Purpura

Researchers

Presenter

  • Brandy Pickens

Principal Investigators

  • Yingying Mao

  • X. Long Zheng

Medical Centers

  • Department of Pathology, The Children's Hospital of Philadelphia, Philadelphia, PA

  • Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

  • Pulmonary/Respiratory Diseases

Disease

  • Thrombotic thrombocytopenic purpura

  • Thrombocytopenia

  • Venous thrombosis

Biomarkers

  • von Willebrand factor

Drug/Treatment

  • thrombospondin-1

  • Evithrom

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim