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201 : Factor XI Deficiency Reduces The Inflammatory Response To Polymicrobial Sepsis In Mice

Researchers

Presenter

  • Charles E. Bane Jr

Principal Investigators

  • Kelli L. Boyd

  • Erik I. Tucker

  • Stephen T. Smiley

  • Andras Gruber

  • David Gailani

Medical Centers

  • Department of Biomedical Engineering, Oregon Health & Science University, Portland, OR

  • Trudeau Institute, Saranac Lake, NY

  • Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN

  • Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN

Locations

  • United States

Companies

  • Aronora Inc.

Study Components

Therapeutic Area

  • Infectious Diseases (ID)

Disease

  • Disseminated intravascular coagulation

  • Hemophilia

  • Venous thrombosis

  • Sepsis

Biomarkers

  • Interleukin 10

  • Tumor necrosis factor

Drug/Treatment

  • Fibrinogen (IV)

  • Evithrom

  • Interleukin-10

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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