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2715 : B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) Specific Copy Number Alterations Are Unique For Progressive Pediatric Chronic Myeloid Leukemia (CML): A Large Cohort Study

Researchers

Presenter

  • Naomi E van der Sligte

Principal Investigators

  • Manuela Krumbholz

  • Agata Pastorczak

  • Jutta Bradtke

  • Markus Metzler

  • Meinolf Suttorp

  • Evelina S De Bont

  • Frank N. van Leeuwen

  • Blanca Scheijen

  • Josephine T Tauer

  • Christina Nowasz

  • Edwin Sonneveld

  • Truuske H de Bock

  • Tiny G Meeuwsen - de Boer

  • Simon V. van Reijmersdal

  • Roland P. Kuiper

Medical Centers

  • Dutch Childhood Oncology Group, The Hague, Netherlands.

  • University Hospital Carl Gustav Carus, Dresden, Germany

  • Department of Urology, Radboud University Medical Center, Nijmegen, Netherlands

  • Laboratory of Pediatric Oncology, Radboud university medical center, Nijmegen, Nijmegen, Netherlands

  • Experimential Rheumatology, Radboud university medical center, Nijmegen, Netherlands

  • Department of Pediatric Hematology and Oncology, University Giessen, Giessen, Germany

  • Pediatric Oncology/Hematology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands

  • Pediatric Oncology/Hematology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands

  • Oncology, Childrens Hosp. of the Univ. of Erlangen, Erlangen, Germany

  • Pediatric Oncology/Hematology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands

Locations

  • Germany

  • Netherlands

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Chronic Myelogenous Leukemia

Biomarkers

  • Paired box 5

  • Cyclin Dependent Kinase Inhibitor 2A

Drug/Treatment

  • Imatinib

  • IkT001

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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