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2671 : High-Grade Pegylated Asparaginase-Related Hepatotoxicity Occurrence In a Pediatric-Inspired Adult Acute Lymphoblastic Leukemia Regimen Does Not Necessarily Predict Recurrent Hepatotoxicity In Subsequent Cycles

Researchers

Presenter

  • Patrick W. Burke

Principal Investigators

  • Ibrahim Aldoss

  • Matthew A. Lunning

  • Vassilios I. Avramis

  • Ann M. Mohrbacher

  • Vinod Pullarkat

  • Martin S. Tallman

  • Dan Douer

Medical Centers

  • Leukemia Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, Weill Cornell Medical College, New York, NY

  • Hematology/Oncology, University of Nebraska Medical Center, Omaha, NE

  • Children's Hospital Los Angeles/University of Southern California, Los Angeles, CA.

  • Lymphoma Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY

  • Department of Pathology, University of Southern California, Los Angeles, CA

  • University of Southern California Keck School of Medicine, Los Angeles, CA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Gastroenterology (GU)

Disease

  • Acute lymphoblastic leukemia

  • Hyperbilirubinemia

  • Pancreatitis

Biomarkers

  • Breakpoint Cluster Region

Drug/Treatment

  • Pegaspargase

  • Oncaspar

  • Asparaginase

  • Vincristine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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