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2622 : Adult B-Cell Precursor Acute Lymphoblastic Leukemia (BC-ALL) Negative For Recurrent Fusion Genes Are Characterized By a High Complex Genetic Heterogeneity Influencing Prognosis

Researchers

Presenter

  • Ilaria Iacobucci

Principal Investigators

  • Margherita Perricone

  • Andrea Ghelli Luserna Di Rora

  • Annalisa Lonetti

  • Antonella Vitale

  • Loredana Elia

  • Viviana Guadagnuolo

  • Nicoletta Testoni

  • Simona Soverini

  • Stefania Paolini

  • Sarah Parisi

  • Chiara Sartor

  • Valentina Robustelli

  • Federica Cattina

  • Domenico Russo

  • Robin Foa

  • Sabina Chiaretti

  • Alexander Kohlmann

  • Giovanni Martinelli

  • Cristina Papayannidis

  • Roberta Zuntini

  • Maria Chiara Abbenante

  • Claudia Venturi

  • Carmen Baldazzi

  • Emanuela Ottaviani

  • Barbara Giannini

Medical Centers

  • Chair of Hematology, Bone Marrow Transplant Unit, University of Brescia, AO Spedali Civili Brescia, Brescia, Italy

  • Munich Leukemia Laboratory, Munich, Germany.

  • Department of Biomedical and Neuromotor Sciences, University of Bologna Italy, Bologna, Italy

  • Seragnoli Institute of Hematology, Bologna University School of Medicine, Bologna, Italy

  • S Orsola-Malpighi Hospital, University of Bologna, Department of Hematology and Oncology L and A Ser gnoli, Bologna, Italy

  • Hematology, University of Brescia, Brescia, Italy

  • Laboratorio Unico Area Vasta Romagna, Pievesestina di Cesena, Italy

  • Institute of Hematology, University of Bologna, Bologna, Italy

  • Bologna University School of Medicine, Bologna, Italy

  • U.O. Genetica Medica, Dip.Scienze Mediche e Chirurgiche - DIMEC, University of Bologna, Bologna, Italy

Locations

  • Germany

  • Italy

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Solid malignancies

Biomarkers

  • Cyclin Dependent Kinase Inhibitor 2A

  • Retinoblastoma protein

  • Histone-lysine N-methyltransferase 2A

  • Tumor protein p53

Drug/Treatment

  • L-Tyrosine

  • TP53

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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