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2586 : Prognostic Impact Of MLL5 transcript Levels On Outcome Of Patients With Acute Promyelocytic Leukemia Treated With All-Trans Retinoic Acid and Anthracycline-Based Chemotherapy: An International Consortium On Acute Promyelocytic Leukemia Study

Researchers

Presenter

  • Antonio R Lucena-Araujo

Principal Investigators

  • Rafael Jacomo

  • Robert E Gallagher

  • Charlotte M. Niemeyer

  • Stanley L. Schrier

  • Martin S Tallman

  • David Grimwade

  • Arnold Ganser

  • Nancy Berliner

  • Raul Ribeiro

  • Francesco Lo-Coco

  • Raul A Melo

  • Bob Lowenberg

  • Miguel A. Sanz

  • Eduardo M Rego

  • Rosane Bittencourt

  • Ricardo Pasquini

  • Katia B. Pagnano

  • Evandro Fagundes

  • Maria de Lourdes L. F. Chauffaille

  • Ana S Lima

  • Hau C. Kwaan

Medical Centers

  • HEMOPE, Recife, Brazil

  • Federal University of Sao Paulo (UNIFESP), Sao Paulo, Brazil

  • Federal University of Rio Grande do Sul, Porto Alegre, Brazil

  • Pediatric Oncology, Hospital Universitari i Politecnic La Fe, Valencia, Spain

  • Lymphoma Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY

  • St. Jude Children's Research Hospital, Memphis, TN

  • Federal University of Minas Gerais, Belo Horizonte, Brazil

  • Division of Hematology, Stanford University, Stanford, CA

  • Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL

  • Albert Einstein College of Medicine, Great Neck, NY

  • Brigham and Women's Hospital, Brookline, MA

  • Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA

  • Kings College London, London, United Kingdom

  • Hematology and Hemotherapy Center, University of Campinas, Campinas, Brazil

  • Division of Paediatric Haematology and Oncology, Department of Paediatrics, University of Freiburg, Freiburg, Germany

  • Medical School of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Brazil

  • Medical School of Ribeirao Preto, USP, Ribeirao Preto, Brazil

  • Hannover Medical School, Hannover, Germany

  • Federal University of Parana, Curitiba, Brazil

  • University of Rome Tor Vergata, Rome, Italy

  • Department of Medical Oncology, VU University Medical Center, Amsterdam, Netherlands

Locations

  • Brazil

  • Italy

  • Netherlands

  • Spain

  • Germany

  • United Kingdom

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

  • Pulmonary/Respiratory Diseases

Disease

  • Acute promyelocytic leukemia

  • Venous thrombosis

Biomarkers

  • Abelson murine leukemia viral oncogene homolog

  • Promyelocytic Leukemia

Drug/Treatment

  • Tretinoin

  • Daunorubicin

  • Idarubicin Hydrochloride

  • Hypaque Injection

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim