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2579 : Reappraisal Of The p16INK4A/Prb Pathway and Telomerase Activity, Markers Of Cell Activation and Aging, In Adult Acute Lymphoblastic Leukemia: A Graall Study

Researchers

Presenter

  • Martine Ffrench

Principal Investigators

  • Regine Catallo

  • Martine Escoffre-Barbe

  • Thibault Leguay

  • Huguet Francoise

  • Fabrice Larosa

  • Sandrine Hayette

  • Adriana Plesa

  • Norbert Ifrah

  • Herve Dombret

  • Gilles Salles

  • Agnes Chassevent

  • Amel Chebel

  • Laurence Baranger

  • Xavier Thomas

  • Marie-Christine Bene

  • Luc M Gerland

  • Aline Schmidt

  • Kheira Beldjord

  • Nathalie Klein

Medical Centers

  • Claude Bernard Lyon University, CNRS UMR ENS - HCL, Lyon-Sud Medicine Faculty,, Oullins, France

  • Claude Bernard Lyon University, CNRS UMR ENS - HCL, Lyon-Sud Medicine Faculty,, Oullins, France

  • department of hematology, Hospices civils de Lyon, Pierre Benite, France

  • Department of Rheumatology, CHRU Besancon, Besancon, France

  • Hospital Saint Antoine, Paris, France

  • Centre Hospitalier Lyon-Sud, Pierre-Benite, France

  • Dermatology, Hopital Saint-Louis, Paris, France

  • Department of Hematology, CHU Nantes, Nantes, France

  • Hematology department 1G, Centre Hospitalier Lyon Sud, Pierre Benite, France

  • Centre Hospitalier Lyon-Sud, Pierre-Benite, France

  • Cytogenetics and molecular biology laboratory, Centre Hospitalier Lyon Sud, Pierre Benite, France

  • Hematology, CHU, Angers, France

  • Department of Hematology, St Louis Hospital, Paris, Paris, France

  • department of hematology, Hospices civils de Lyon, Pierre Benite, France

  • Service des Maladies du Sang, CHU Angers, Angers, France

  • Hematology Clinic, CHU Nantes, Nantes, France

  • Department of Hematology, CHU, Bordeaux,, Bordeaux, France

  • Hematology, CHU Rennes, Rennes, France

  • hematology department, Centre hospitalier Purpan, Toulouse, France

Locations

  • France

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Neurogenic locus notch homolog protein 1

  • Breakpoint Cluster Region

  • Telomerase

Drug/Treatment

  • Allopurinol

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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