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2552 : The Genomic Landscape Of Lineage Switch Acute Leukemia

Researchers

Presenter

  • Olaf Heidenreich

Principal Investigators

  • Simon Bomken

  • Helen J Blair

  • Dan Swan

  • Bronia Baker

  • Peter Carey

  • Nick Bown

  • David Bourn

  • Paul Evans

  • Roderick Skinner

  • Simon Bailey

  • Dan Williamson

  • Vikki Rand

  • James Allan

  • Sarah E Fordham

  • Hesta McNeill

  • Claus Meyer

  • Rolf Marschalek

  • Josef Vormoor

  • Andrew Hall

  • Julie Irving

Medical Centers

  • Northern Institute for Cancer Research Newcastle University, Newcastle, United Kingdom

  • Newcastle University, Newcastle upon Tyne, United Kingdom

  • Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle-upon-Tyne, United Kingdom

  • Haematological Malignancy Diagnostic Service, St. James's University Hospital, Leeds, United Kingdom

  • Northern Institute for Cancer Research Newcastle University, Newcastle, United Kingdom

  • OCTO, Oxford, United Kingdom

  • DCAL / Institute of Pharmaceutical Biology, Goethe University, Frankfurt, Germany

  • Newcastle Cancer Centre at the Northern Institute for Cancer Research, Newcastle University, Newcastle, United Kingdom

  • Newcastle University, Newcastle upon Tyne, United Kingdom

  • Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle-upon-Tyne, United Kingdom

Locations

  • Germany

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Acute myelocytic leukemia

  • Acute Leukemia

  • B-cell acute lymphoblastic leukemia

Biomarkers

  • AF4/FMR2 Family Member 1

  • Paired box 5

  • Histone-lysine N-methyltransferase 2A

  • Lysine acetyltransferase 6A

  • Microsatellite instability

  • Chromodomain-helicase-DNA-binding protein 4

Drug/Treatment

  • folitixorin calcium

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim