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2545 : Loss Of BTG1 Function Promotes ETV6-RUNX1-Mediated Leukemic Transformation

Researchers

Presenter

  • Esther J.H. Tijchon

Principal Investigators

  • Liesbeth van Emst

  • Dorette van Ingen Schenau

  • Laurens T. van der Meer

  • Owen Williams

  • Peter M. Hoogerbrugge

  • Blanca Scheijen

  • Frank N. van Leeuwen

Medical Centers

  • Department of Urology, Radboud University Medical Center, Nijmegen, Netherlands

  • Laboratory of Pediatric Oncology, Radboud university medical center, Nijmegen, Nijmegen, Netherlands

  • Experimential Rheumatology, Radboud university medical center, Nijmegen, Netherlands

  • Molecular Hematology and Cancer Biology, Institute of Child Health, London, United Kingdom

Locations

  • United Kingdom

  • Netherlands

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Protein Arginine Methyltransferase 1

  • Fms related tyrosine kinase 3 Ligand

  • Interleukin-7

Drug/Treatment

  • Arginine hydrochloride

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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