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2543 : Thymic Stromal Lymphopoeitin Signaling Contributes To Increased Risk Of Relapse Of Pediatric Acute Lympoblastic Leukemia Through Enhanced Survival Of Leukemic Cells That Overexpress Thymic Stromal Lymphopoeitin Receptor

Researchers

Presenter

  • Christopher D Chien

Principal Investigators

  • Matthew Kreitman

  • Haiying Qin

  • Terry J Fry

Medical Centers

  • Yeshiva University, New York, NY.

  • Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Solid malignancies

Biomarkers

  • Annexin V

  • Breakpoint Cluster Region

  • Interleukin-7

  • Kallikrein Related Peptidase 11

  • Signal transducer and activator of transcription 5

Drug/Treatment

  • Dexamethasone

  • Dekpak 13 Day Taperpak

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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