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2529 : Vincristine and Prednisolone Combination Reduces MDR1 and Microenvironment-Mediated Treatment Resistance In Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Nan Jiang

Principal Investigators

  • Zhenhua Li

  • Grace Shimin Koh

  • Shirley K.Y. Kham

  • Allen Eng Juh Yeoh

Medical Centers

  • Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

Locations

  • Singapore

Companies

  • N/A

Study Components

Therapeutic Area

  • Congenital disorder

  • Obstetrics/Gynecology

Disease

  • Acute lymphoblastic leukemia

  • Mismatch repair deficiency

  • Solid malignancies

  • Twin Anaemia Polycyth aemia Syndrome

Biomarkers

  • ATP Binding Cassette Transporter B1

Drug/Treatment

  • Glucocorticoid

  • Methotrexate

  • Prednisolone

  • Vincristine

  • Calan

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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