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2508 : Key Nodes In FLT3 Dependent Signaling Determine Growth and Survival Of Childhood Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Kevin Dierck

Principal Investigators

  • Ina Siekmann

  • Sebastian Prall

  • Florian Beck

  • Irmela Jeremias

  • Albert Sickmann

  • Martin A. Horstmann

Medical Centers

  • Department of Bioanalytics, ISAS, Dortmund, Germany

  • Department of Gene Vectors, Helmholtz Center Munich, Munich, Germany

  • Department of Pediatric Hematology and Oncology, University Medical Center Eppendorf, Hamburg, Germany

  • Research Institute Childrens Cancer Center and Clinic of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

Locations

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Breakpoint Cluster Region

  • Platelet-derived growth factor receptor

  • Fms related tyrosine kinase 3

Drug/Treatment

  • L-Tyrosine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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