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THU0247 : The Effect of Hydroxychloroquine and IRAK4 Inhibition on The IFN-A and TNF-A Production Induced by Sle Related Immune Complexes

Researchers

Presenter

  • K. Hjorton

Principal Investigators

  • N. Hagberg

  • O. Berggren

  • J. Mo

  • J. Sandling

  • M.-L. Eloranta

  • L. Ronnblom

Medical Centers

  • AstraZeneca, Molndal, Sweden

Locations

  • Sweden

Companies

  • N/A

Study Components

Therapeutic Area

  • N/A

Disease

  • N/A

Biomarkers

  • Natural Killer cells

  • Peripheral blood mononuclear cell

  • Interleukin 1

  • Interleukin-1 receptor-associated kinase 4

  • Tumor necrosis factor

Drug/Treatment

  • Hydroxychloroquine

  • IFN-lambda

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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