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OP0289 : MICRORNAS AS POTENTIAL REGULATORS OF MONOCYTE DIFFERENTIATION AND FUNCTION IN HEART FIBROSIS IN SYSTEMIC SCLEROSIS

Researchers

Presenter

  • M. Rudnik

Principal Investigators

  • M. Stellato

  • P. Blyszczuk

  • E. Pachera

  • R. Dobrota

  • B. Maurer

  • K. Klingel

  • J. Henes

  • K. Sotlar

  • O. Distler

  • G. Kania

Medical Centers

  • Cardioimmunology, Center of Molecular Cardiology, University of Zurich, Schlieren, Switzerland

  • Institute of Pathology, Ludwig-Maximilians-University, Munich, Germany

Locations

  • Germany

  • Switzerland

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

Disease

  • Dilated cardiomyopathy

  • Myocardial fibrosis

  • Scleroderma

  • Heart muscle disease

Biomarkers

  • microRNA-155

  • microRNA-29b

  • Cluster of Differentiation 14

  • Interleukin 10

  • Interleukin 13

  • Interleukin 4

  • microRNA-10b

Drug/Treatment

  • DE-074

  • miR155

  • Interleukin-10

  • IL-4

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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