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1247 : Reduction of oxidative stress promotes daunorubicin resistance in acute lymphoblastic leukemia cells

Researchers

Presenter

  • Xia Sheng

Principal Investigators

  • Jonathan Tucci

  • Steven D. Mittelman

Medical Centers

  • Children's Hosp Los Angeles, Los Angeles, CA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Solid malignancies

Biomarkers

  • Abelson murine leukemia viral oncogene homolog

  • Breakpoint Cluster Region

  • Proto-oncogene tyrosine-protein kinase ROS

Drug/Treatment

  • N-acetylcysteine

  • Daunorubicin

  • Cysteine Hydrochloride

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final