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27 : Aberrant Expression of the Stem Cell microRNA-126 Induces B Cell Malignancy

Researchers

Presenter

  • Silvia Nucera

Principal Investigators

  • Francesco Boccalatte

  • Andrea Calabria

  • Bernhard Gentner

  • Tiziana Plati

  • Cristiana Fanciullo

  • Jose Manteiga

  • Fabrizio Benedicenti

  • Fabio Ciceri

  • Maurilio Ponzoni

  • Eugenio Montini

  • Luigi Naldini

Medical Centers

  • Department of Hematology and Stem Cell Transplantation, San Raffaele, Milano, Italy

  • Department of Functional Genomics, Vita Salute San Raffaele university, Milano, Italy

  • Division of Regenerative Medicine, Stem Cells and Gene Therapy, San Raffaele Telethon Institute for Gene Therapy, Milano, Italy

  • Department of Pathology, San Raffaele, Milano, Italy

Locations

  • Italy

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Lymphomas

  • B-cell acute lymphoblastic leukemia

Biomarkers

  • p53

  • Cluster of Differentiation 34

  • MicroRNA 126

  • microRNA-126

Drug/Treatment

  • Tetracycline

  • Doxycycline

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final