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1237 : CNOT1 Microrna Single Nucleotide Polymorphism (SNP) Determines the Occurrence of Methotrexate Related Mucositis in Pediatric Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Natanja Oosterom

Principal Investigators

  • Angela Guttierez-Camino

  • Marissa Den Hoed

  • Elixabet Lopez-Lopez

  • Saskia MF Pluijm

  • Rob Pieters

  • Robert de Jonge

  • Wim JE Tissing

  • Africa Garcia-Orad

  • Sandra G Heil

  • Marry M van den Heuvel-Eibrink

Medical Centers

  • Princess Maxima Center for Pediatric Oncology, Netherlands

  • Department of Medical Oncology, University Medical Center Groningen, Groningen, Netherlands

  • Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital, Rotterdam, Netherlands

  • Department of Genetics, Physical Anthropology and Animal physiology, Faculty of Medicine and Odontology, University of the Basque Country (UPV/EHU), Leioa, Spain

  • Princess Maxima Center for Pediatric Oncology, Netherlands

  • Department of Clinical Chemistry, Erasmus Medical Center, Rotterdam, Netherlands

Locations

  • Spain

  • Netherlands

Companies

  • N/A

Study Components

Therapeutic Area

  • Central Nervous System (CNS)

Disease

  • Acute lymphoblastic leukemia

  • Mucositis

  • Solid malignancies

  • Trauma

Biomarkers

  • N/A

Drug/Treatment

  • Methotrexate

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final