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1324 : Clinical Activity and Persistence of Anti-CD22 Chimeric Antigen Receptor in Children and Young Adults with Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL)

Researchers

Presenter

  • Terry J. Fry

Principal Investigators

  • Maryalice Stetler-Stevenson

  • Nirali N Shah

  • Constance M. Yuan

  • Bonnie Yates

  • Cindy Delbrook

  • Ling Zhang

  • Daniel W. Lee III

  • David Stroncek

  • Crystal L. Mackall

Medical Centers

  • Laboraory of Pathology, National Cancer Institute, Gaithersburg, MD

  • Department of Transfusion Medicine, Clinical Center, National Institutes of Health, Bethesda, MD

  • Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD

  • Radiation Oncology Branch, National Cancer Institute at the National Institutes of Health, Bethesda, MD

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Cytokine release syndrome

  • Hematological malignancies

Biomarkers

  • Breakpoint Cluster Region

  • Cluster of Differentiation 19

  • Twist-related protein 1

  • Cerebrospinal fluid

Drug/Treatment

  • Cyclophosphamide

  • Cyclophosphamide Injection

  • fludarabine tablet

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final