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1285 : L-Asparaginase More Effectively Targets Leukemic Cells with Low Glycolytic Activity

Researchers

Presenter

  • Simcikova Marketa

Principal Investigators

  • Alena Pecinova

  • Ivana Hermanova

  • David Pajuelo Reguera

  • Katerina Rejlova

  • Marketa Zaliova

  • Jan Stuchly

  • Tomas Mracek

  • Jan Trka

  • Julia Starkova

Medical Centers

  • Department of Bioenergetics, Institute of Physiology of the Czech Academy of Sciences, Prague, Czech Republic

  • Childhood Leukaemia Investigation Prague, Department of Pediatric Hematology/Oncology, 2nd Faculty of Medicine, Charles University Prague, Prague, Czech Republic

  • Childhood Leukaemia Investigation Prague, Department of Pediatric Hematology/Oncology, 2nd Faculty of Medicine, Charles University Prague, Prague, Czech Republic

Locations

  • Czech Republic

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Chronic Myelogenous Leukemia

  • Tuberculosis

  • Solid malignancies

  • T-cell acute lymphoblastic leukemia

Biomarkers

  • Breakpoint Cluster Region

  • Glucose transporter 1

Drug/Treatment

  • Asparaginase

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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