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1429 : Crebbp Knockdown Does Not Impact on Glucocorticoid Induced Apoptosis in Childhood Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Zach Dixon

Principal Investigators

  • Julie A.E. Irving

  • Lindsay Nicholson

Medical Centers

  • Haematological Sciences, ICM, Newcastle University, Newcastle, United Kingdom

  • Northern Institute for Cancer Research Newcastle University, Newcastle, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Mismatch repair deficiency

  • Solid malignancies

Biomarkers

  • B-cell lymphoma 6

  • Breakpoint Cluster Region

  • p53

  • CREB-binding protein

  • C-X-C motif chemokine receptor 4

  • Cyclic adenosine monophosphate

  • Dual specificity phosphatase 5

  • FK506-binding protein 5

  • Glucocorticoid sensitivity

  • MAPK Interacting Serine/Threonine Kinase 2

Drug/Treatment

  • Glucocorticoid

  • Dexamethasone

  • Dekpak 13 Day Taperpak

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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