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1422 : Integrated DNA/RNA Profiling for Somatic Alterations in Adult B-Cell ALL

Researchers

Presenter

  • Franck Rapaport

Principal Investigators

  • Jay Patel

  • Jie He

  • Mark R Litzow

  • Peter H. Wiernik

  • Anthony H. Goldstone

  • Timothy A Brennan

  • Michelle Nahas

  • Sohail Balassubramanian

  • Geoff Otto

  • Doron Lipson

  • Phil Stephens

  • Vincent A. Miller

  • Janis Racevskis

Medical Centers

  • Clinical Genetics Service, Memorial Sloan-Kettering Cancer Center, New York, NY

  • Foundation Medicine, Inc, Cambridge, MA

  • Department of Medicine, Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY

  • Foundation Medicine, Inc, Cambridge, MA

  • Weill Cornell Medical College, New York, NY

  • Department of Medicine (Oncology), Albert Einstein College of Medicine, Montefiore Medical Center, New York, NY

  • Department of Oncology, Montefiore Medical Center North Division, Bronx, NY

  • Abramson Cancer Center of the University of Pennsylvania, Philadelphia, PA

  • Memorial Sloan Kettering Cancer Center, Port Washington, NY

  • Memorial Sloan Kettering Cancer Center, Port Washington, NY

  • Cancer Center, The North Division of Montefiore Medical Center, Bronx, NY

  • Shaare Zedek Medical Center, Jerusalem, Israel

  • Memorial Sloan Kettering, New York, NY

Locations

  • United States

  • Israel

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Hematological malignancies

  • B-cell acute lymphoblastic leukemia

  • Solid malignancies

Biomarkers

  • Paired box 5

  • Platelet Derived Growth Factor Receptor Beta

  • Cyclin Dependent Kinase Inhibitor 2A

  • Cyclin Dependent Kinase Inhibitor 2B

  • DNA methyltransferase 3 alpha

  • GTPase Nras

  • Histone-lysine N-methyltransferase 2A

  • KRAS proto-oncogene, GTPase

  • Tet methylcytosine dioxygenase 2

  • DNA methylation

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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