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99 : Allogeneic T-Cells Expressing an Anti-CD19 Chimeric Antigen Receptor Cause Remissions of B-Cell Malignancies after Allogeneic Hematopoietic Stem Cell Transplantation without Causing Graft-Versus-Host Disease

Researchers

Presenter

  • Jennifer N Brudno

Principal Investigators

  • Robert Somerville

  • Victoria Shi

  • Steven Feldman

  • Alex Iwamoto

  • Roger Kurlander

  • Jeremy J. Rose

  • David C. Halverson

  • Daniel H. Fowler

  • Dennis D. Hickstein

  • Juan C. Gea-Banacloche

  • Steven Z. Pavletic

  • Andre Goy

  • Tangying L Lu

Medical Centers

  • Center for Cancer Research, National Cancer Institute, Bethesda, MD

  • Surgery Branch, NIH, NCI, Bethesda, MD

  • Hematology Section, Department of Laboratory Medicine, NIH Clinical Center, Bethesda, MD

  • Experimental Transplantation and Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD

  • Frederick National Laboratory for Cancer Research, Clinical Monitoring Research Program, Leidos Biomedical Research, Inc., Frederick, MD

  • Hematology Section, Department of Laboratory Medicine, NIH Clinical Center, Bethesda, MD

  • John Theurer Cancer Centre, Hackensack University Medical Center, Hackensack, NJ

  • Experimental Transplantation and Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD

  • ETIB, NIH, NCI, Bethesda, MD

  • Surgery Branch, NIH, NCI, Bethesda, MD

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Autoimmune (AI)

Disease

  • Diffuse large B-cell lymphoma

  • Acute lymphoblastic leukemia

  • Chronic Lymphocytic Leukemia

  • Graft-versus-host disease

  • Mantle cell lymphoma

  • B cell lymphomas

  • Follicular lymphoma

  • Arrhythmia

  • Lymphomas

Biomarkers

  • Breakpoint Cluster Region

  • Ph chromosome

  • Cluster of Differentiation 4

  • Programmed cell death protein 1

  • Cluster of differentiation 8A

  • Coxsackie Virus And Adenovirus Receptor

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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