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967 : Myosin-IIa Is Required for Leukemia Cell Extravasation and Its Inhibition Reduces Leukemia Dissemination and Prolongs Survival in a Mouse Model of Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Jordan Jacobelli

Principal Investigators

  • Eric Wigton

  • Scott B Thompson

Medical Centers

  • Department of Biomedical Research, National Jewish Health, Denver, CO.

  • Immunology and Microbiology, University of Colorado School of Medicine, Denver, CO

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • B-cell acute lymphoblastic leukemia

Biomarkers

  • Myosin Heavy Chain 8

  • Ph chromosome

  • Stromal cell-derived factor 1

Drug/Treatment

  • L-Tyrosine

  • CXCL12

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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