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1392 : Increased Von Willebrand Factor and High Circulating Placental Growth Factor Correlate with Inflammation and Iron Overload in Patients with Compound Heterozygous Sickle Cell and Beta-Thalassemia

Researchers

Presenter

  • Ersi Voskaridou

Principal Investigators

  • Katerina Larrisi

  • Marianna Politou

  • Veroniki Komninaka

  • Filia Apostolakou

  • Chrysanthi Skevaki

  • Maria Giannaki

  • Ioannis Papassotiriou

  • Evangelos Terpos

Medical Centers

  • Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Alexandra General Hospital, Athens, Greece

  • Department of Microbiology, Aghia Sophia Childrens Hospital, ATHENS, Greece

  • Department of Clinical Biochemistry, Aghia Sophia Childrens Hospital, Athens, Greece

  • Sotiria General Hospital, Athens, Greece

  • Laboratory of Hematology and Blood Bank Unit, Aretaieio Hospital, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

  • Thalassemia and Sickle Cell Disease Center, Laikon University General Hospital, Athens, Greece

Locations

  • Greece

Companies

  • N/A

Study Components

Therapeutic Area

  • Blood/haematological Diseases

Disease

  • Vasodilation dysfunction

  • Sickle cell anemia

  • Beta-thalassemia

  • Hemochromatosis

  • Thalassemia

  • Coronary Artery Disease

  • Anemia

Biomarkers

  • Placental growth factor

  • Ferritin

  • High sensitivity C-reactive protein

  • Lactate dehydrogenase

  • Stearoyl-CoA desaturase

  • von Willebrand factor

Drug/Treatment

  • Hydroxycarbamide

  • Nitric oxide

  • Hemostatic Solution

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final