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1070 : IFITM3 (CD225) Regulates CD19 Surface Expression and CD19-Mediated Activation of PI3K Signaling in Pre-B Acute Lymphoblastic Leukemia Cells

Researchers

Presenter

  • Jae-Woong Lee

Principal Investigators

  • Huimin Geng

  • Zhengshan Chen

  • Eugene Park

  • Angela Park

  • Lars Klemm

  • Charles Bailey

  • Markus Muschen

Medical Centers

  • Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA

  • Department of Microbiology and Immunobiology, Harvard Medical School, New England Primate Research Center, Southborough, MA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

Biomarkers

  • Breakpoint Cluster Region

  • p53

  • cMYC

  • Complement component receptor 2

  • Coxsackie Virus And Adenovirus Receptor

  • Interferon-induced transmembrane protein 1

Drug/Treatment

  • Afimoxifene

  • Adriamycin injection

  • Interferon

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final