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895 : NOTCH1 Transcriptionally Activates Deptor and Promotes AKT Activation in Acute T-Cell Lymphoblastic Leukemia

Researchers

Presenter

  • Hudan Liu

Principal Investigators

  • Yufeng Hu

  • Hexiu Su

  • Qi Ye

  • Zhaojing Wang

  • Liang Huang

  • Qian Wang

  • Suning Chen

  • Jianfeng Zhou

  • Shuangyou Liu

  • Guoliang Qing

Medical Centers

  • Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

  • Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

  • Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

  • Department of Oncology, the First Affiliated Hospital of Soochow University, Suzhou, China

Locations

  • China

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Hematological malignancies

  • Multiple Myeloma

  • Solid malignancies

  • T-cell acute lymphoblastic leukemia

Biomarkers

  • DEP domain-containing mTOR-interacting protein

  • Serine/threonine-protein kinase mTOR

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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