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SAT-0988 : Control of Oral Advanced Glycation Endproducts (AGEs) By Sevelamer Carbonate Improves Glucose Metabolism and Albuminuria in Stage 2-4 Diabetic Kidney Disease (DKD)

Researchers

Presenter

  • Gary E Striker

Principal Investigators

  • Elena Yuberro-Serrano

  • Leonid Poretsky

  • Helen Vlassara

Medical Centers

  • Mount Sinai Hospital, New York, NY

  • Mount Sinai Beth Israel, New York, NY

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Endocrine/metabolic Diseases (ME)

  • Genetic Disorder

Disease

  • Diabetic nephropathy

  • Renal disease

  • Albuminuria

  • Diabetes

  • Type 2 diabetes mellitus

Biomarkers

  • Advanced Glycosylation End-Product Specific Receptor

  • Hemoglobin A1c

  • Hepatocyte growth factor receptor

  • TNF Receptor Superfamily Member 1A

  • Vascular cell adhesion molecule 1

  • Sirtuin 1

Drug/Treatment

  • Sevelamer carbonate

  • Metformin Hydrochloride

  • MK8970

  • Sevelamer

Outcome

  • N/A

Study Design

  • open label

  • randomized

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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