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e16032 : Overcoming resistance mechanisms in a study of cabozantinib (C) plus docetaxel (D) and prednisone (P) in metastatic castrate-resistant prostate cancer (mCRPC).

Researchers

Presenter

  • Fatima Karzai

Principal Investigators

  • Ravi Amrit Madan

  • Marc Robert Theoret

  • Seth M. Steinberg

  • Jane B. Trepel

  • John Joseph Wright

  • Douglas K. Price

  • James L. Gulley

  • William Douglas Figg

  • Guinevere Chun

  • Anna Couvillon

  • Nancy Harold

  • Clara Chen

  • Nancy Ann Dawson

  • Andrea Borghese Apolo

  • William L. Dahut

  • Philip M. Arlen

  • Julius Strauss

Medical Centers

  • Lombardi Comprehensive Cancer Center, Washington, DC

  • Gastrointestinal Malignancies Section, Center for Cancer Research, National Cancer Institute at the National Institutes of Health, Bethesda, MD

  • National Human Genome Research Institute, National Institutes of Health, Bethesda, MD

  • Natl Cancer Inst, Bethesda, MDClinical Pharmacology Program, National Cancer Institute, National Institutes of Health, Bethesda, MDNatl Cancer Inst NIH, Bethesda, MD

  • Radiation Oncology Branch, National Cancer Institute at the National Institutes of Health, Bethesda, MD

  • Gastrointestinal Malignancies Section, Center for Cancer Research, National Cancer Institute at the National Institutes of Health, Bethesda, MD

  • Biostatistics and Data Management Section, National Cancer Institute at the National Institutes of Health, Bethesda, MD

  • Department of Transfusion Medicine, Clinical Center, National Institutes of Health, Bethesda, MD

  • National Human Genome Research Institute, National Institutes of Health, Bethesda, MD

  • Clinical Pharmacology Program, National Cancer Institute at the National Institutes of Health, Bethesda, MD

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

  • Urology

Disease

  • Metastatic castration-resistant prostate cancer

Biomarkers

  • N/A

Drug/Treatment

  • Cabozantinib

  • Prednisone

  • Docetaxel

Outcome

  • N/A


Study Design

  • randomized

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A