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2560 : A phase I study of metformin and chemotherapy in solid tumors.

Researchers

Presenter

  • Athena Kritharis

Principal Investigators

  • Jennifer Caplain

  • Robert Martell

  • Wasif M. Saif

  • Shrikar RajagopAlElizabeth Grimm

  • Philip N. Tsichlis

Medical Centers

  • Molecular Oncology Research Institute, Tufts Medical Ctr., Boston, MA.

  • Tufts Medical Center, Boston, MADivision of Hematology Oncology, Tufts Medical Center, Boston, MA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Solid malignancies

Biomarkers

  • AMP-activated protein kinase

  • Peripheral blood mononuclear cell

Drug/Treatment

  • Metformin Hydrochloride

Outcome

  • Positive

Study Design

  • randomized

Phase

  • I

Study Id's

  • NCT01442870

Sponsors

  • N/A

Result

  • Final

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