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1048 : First safety results of an international phase II study evaluating oral vinorelbine as a single agent as first-line chemotherapy for metastatic breast cancer patients with bone metastases (NorBreast-228 trial).

Researchers

Presenter

  • Guenther G. Steger

Principal Investigators

  • Adriana Dominguez

  • Corinne Veyret

  • Sheyla Garcia

  • Joan Dorca Ribugent

  • Christian Marth

  • Alexey Manikhas

  • Marco Benasso

  • Svetlana Protsenko

  • Gustavo Villanova

  • Iwona Glogowska

  • Nicole Tubiana-Mathieu

  • Martin Pecherstorfer

  • Andrea Ardizzoia

  • Philippe Bougnoux

  • Maria Blasinska-Morawiec

  • Enrique Espinosa

  • Odile Switsers

  • Francesco Giotta

Medical Centers

  • Department of Medical Oncology, Centre Henri Becquerel, Rouen, France

  • Hospital Universitario La Paz, Madrid, Spain

  • Memorial Cancer Center, Warsaw, Poland

  • Wojewodzki Szpital Specjalistyczny im Kopernika, Lodz, Poland

  • Department for Medicine I/Clinical Division of Oncology, Medical University of Vienna, Vienna, Austria

  • NN Petrov Research Institute of Oncology, St Petersburg, Russia

  • Centre Francois Baclesse, Caen, France

  • Institut Catala de Oncologia, Girona, Spain

  • Department of Medical Oncology, CHU Bretonneau, Tours, France

  • Cancerologia de Queretaro, Queretaro, Mexico

  • Hospital A. Manzoni, Lecco, Italy

  • City Clinical Oncology Dispensary, St. Petersburg, Russia

  • Hospital J. Graham Casas, Villahermosa, MexicoMedical University of Innsbruck, Innsbruck, Austria

  • Centre Hospitalier Universitaire de Limoges, Limoges, France

  • Landesklinikum, Krems, Austria

  • Institut de Recherche Pierre Fabre, Boulogne, France

  • Russian Research Centre of Roentgenoradiology, Moscow, Russia

  • National Cancer Institute, Bari, BA, Italy

  • Ospedale San Paolo, Savona, Italy

Locations

  • Italy

  • Austria

  • Poland

  • Spain

  • Mexico

  • France

  • Russia

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Breast cancer

  • Bone metastases

  • Solid malignancies

Biomarkers

  • Human epidermal growth factor receptor 2

Drug/Treatment

  • Vinorelbine

Outcome

  • Positive

Study Design

  • N/A

Phase

  • II

Study Id's

  • N/A

Sponsors

  • Laboratoires Pierre Fabre

Result

  • Final

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