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5631 : Personal neoantigen-targeting vaccination generates neoepitope-specific T cell responses in tumors of patients with glioblastoma

Researchers

Presenter

  • Derin B. Keskin

Principal Investigators

  • Annabelle Anandappa

  • Jing Sun

  • Nathan D. Mathewson

  • Sachet A. Shukla

  • Evisa Gjini

  • Shuqiang Li

  • Letitia Li

  • Anita Giobbie-Hurder

  • Phuong M. Le

  • Zhuting Hu

  • Wandi Zhang

  • Oriol Olive

  • Christine McCluskey

  • Heather Daley

  • Patrick Y. Wen

  • Antonio E. Chiocca

  • Maegan Harden

  • Niall Lennon

  • Stacey Gabriel

  • Gad Getz

  • Donna Neuberg

  • Jerome Ritz

  • Eric S. Lander

  • Aviv Regev

  • Kai Wucherpfennig

  • Mario Suva

  • Edward F. Fritsch

  • Rodig Scott

  • Keith L. Ligon

  • Kenneth J. Livak

  • Hacohen Nir

  • Patrick A. Ott

  • Catherine J. Wu

  • David A. Reardon

Medical Centers

  • Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA

  • Broad Institute, Cambridge, MA

  • Massachusetts General Hospital, Boston, MA

  • Neon Therapeutics, Inc., Cambridge, MA

  • Brigham and Women's Hospital and Harvard Medical School, Boston, MA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • N/A

Biomarkers

  • O-6-methylguanine DNA methyltransferase

  • Cluster of Differentiation 4

  • Cluster of differentiation 8A

Drug/Treatment

  • Dexamethasone

  • Dekpak 13 Day Taperpak

  • Interferon

  • Poly-ICLC

Outcome

  • N/A

Study Design

  • N/A

Phase

  • I

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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