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S4-02 : The Y537S ESR1 mutation is a dominant driver of distant ER-positive breast cancer metastasis

Researchers

Presenter

  • SAW Fuqua

Principal Investigators

  • G Gu

  • Y Rechoum

  • L Gelsomino

  • DJ Dustin

  • A Corona-Rodriguez

  • AR Beyer

  • SM Pejerrey

  • M Gao

  • A Tsimelzon

  • L Tian

  • X Zhang

  • C Nagi

  • S Ando

Medical Centers

  • 1.MD Anderson Cancer Center, Houston, TX

  • Baylor College of Medicine, Houston, TX

  • University of Calabria, Rende, Italy

Locations

  • United States

  • Italy

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Breast cancer

  • Lung Cancer

  • Solid malignancies

Biomarkers

  • Cadherin 1

  • Estrogen Receptor 1

  • Snail Family Transcriptional Repressor 1

  • Solute Carrier Family 22 Member 3

  • Twist-related protein 1

Drug/Treatment

  • Fulvestrant

  • Palbociclib

  • Everolimus

  • Tamoxifen

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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