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5153 : Dual inhibition of STAT3 and IL-8 pathways as a novel therapeutic approach in osteosarcoma

Researchers

Presenter

  • Yang Cao

Principal Investigators

  • Hui Xiao

  • Xiaojuan Wu

  • Jiayuh Lin

Medical Centers

  • The Research Institute at Nationwide Children's Hospital, Columbus, OH

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Osteosarcoma

  • Solid malignancies

Biomarkers

  • Interleukin 6

  • Interleukin-8

  • Signal transducer and activator of transcription 3

Drug/Treatment

  • Trametinib

  • LY2228820

  • AZD-6244

  • IL-11

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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