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5133 : Targeting the eicosanoid 20-HETE suppresses pancreatic cancer growth and metastasis through regulation of inflammation

Researchers

Presenter

  • Yael Gus-Brautbar

Principal Investigators

  • Julia Piwowarski

  • Jessica A. Casper

  • Diane R. Bielenberg

  • Jennifer Cheng

  • Birgitta Schmidt

  • Bruce D. Hammock

  • Darryl C. Zeldin

  • Mark W. Kieran

  • Dipak Panigrahy

Medical Centers

  • Center for Vascular Biology Research and Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA

  • Vascular Biology Program, Boston Childrens Hospital, Harvard Medical School, Boston, MA

  • Laboratory of Respiratory Biology, NIH-NIEHS, Research Triangle Park, NC

  • Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

  • Department of Entomology and Cancer Research Center, UC-Davis, Davis, CA

  • Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Pancreatic cancer

  • Solid malignancies

Biomarkers

  • Colony stimulating factor 1

  • Epoxyeicosatrienoic acids

Drug/Treatment

  • Hydroxyeicosatetraenoic acid

  • Gemcitabine

  • HET0016

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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