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4902 : A mouse GITRL fusion protein drives T-cell activation and antitumor activity in preclinical mouse models of cancer

Researchers

Presenter

  • Rebecca Leyland

Principal Investigators

  • Amanda Watkins

  • Kathy A. Mulgrew

  • Lisa Bamber

  • Natalie J. Tigue

  • Emily Dick

  • Nick Holoweckyj

  • Lesley Young

  • Michelle Morrow

  • Scott A. Hammond

  • Ching Ching Leow

  • Robert W. Wilkinson

  • Ross Stewart

Medical Centers

  • MedImmune, Cambridge, United Kingdom

  • MedImmune, Gaithersburg, MD

Locations

  • United States

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Solid malignancies

Biomarkers

  • Cluster of Differentiation 4

  • Proliferation marker protein Ki-67

  • Cluster of differentiation 8A

  • Immunoglobulin G

  • T-cell function

Drug/Treatment

  • N/A

Outcome

  • N/A


Study Design

  • Pharmacodynamics

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A