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4865 : Metformin improves multiple cytokine producing ability of exhausted peripheral CD8+ T cells of cancer patients

Researchers

Presenter

  • Mototsugu Watanabe

Principal Investigators

  • Shingo Eikawa

  • Takenori Uehara

  • Yuki Kunisada

  • Shinichi Toyooka

  • Shinichiro Miyoshi

  • Heiichiro Udono

Medical Centers

  • Okayama University Graduate School, Okayama, Japan

Locations

  • Japan

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Solid malignancies

Biomarkers

  • Peripheral blood mononuclear cell

  • Programmed cell death protein 1

  • Cluster of differentiation 8A

  • Interleukin-2

Drug/Treatment

  • Metformin Hydrochloride

  • lonomycin

  • IFN-lambda

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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