// App-Quantinova.ai

4857 : Design and biological evaluation of substituted pyrrolo[3,2-d]pyrimidines as dual acting RTK and microtubule targeting agents

Researchers

Presenter

  • Aleem Gangjee

Principal Investigators

  • Khushbu Shah

  • Nicholas Dybdal-Hargreaves

  • Susan Mooberry

  • Anja Bastian

  • Michael Ihnat

Medical Centers

  • Duquesne University, Pittsburgh, PA

  • UT Health Science Center, San Antonio, TX

  • The University of Oklahoma College of Pharmacy, Oklahoma, OK.

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

Disease

  • Solid malignancies

  • PDGFRA rearrangement

Biomarkers

  • Aldo-Keto Reductase Family 1 Member B

  • Epidermal growth factor receptor

  • Kinase Insert Domain Receptor

Drug/Treatment

  • Paclitaxel

Outcome

  • N/A


Study Design

  • Pharmacokinetics

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A