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4660 : Inhibition of p38 enhances ERK inhibitor efficacy in pancreatic ductal adenocarcinoma

Researchers

Presenter

  • Meagan B. Ryan

Principal Investigators

  • Kirsten L. Bryant

  • Tikvah K. Hayes

  • Swapnil Kher

  • Kris C. Wood

  • Ahmed A. Samatar

  • Adrienne D. Cox

  • Channing J. Der

Medical Centers

  • University of North Carolina, Chapel Hill, NC

  • Duke University, NC

  • Discovery Oncology Merck Research Laboratories, MA.

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Pancreas ductal adenocarcinoma

  • Solid malignancies

  • Microphthalmia, syndromic, 9

Biomarkers

  • Mitogen-activated protein kinase

  • Mitogen-activated protein kinase 14

  • Mitogen-activated protein kinase 3

  • Extracellular signal-regulated kinase

  • Heat shock protein 27

  • KRAS proto-oncogene, GTPase

Drug/Treatment

  • LY2228820

  • SCH772984

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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