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4655 : Iron chelation inhibits mTORC1 signaling in tumor cells

Researchers

Presenter

  • Chaowei Shang

Principal Investigators

  • Hongyu Zhou

  • Shile Huang

Medical Centers

  • LSUHSC - Shreveport, Shreveport, LA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Rhabdomyosarcoma

  • Hemochromatosis

  • Lung Cancer

  • Solid malignancies

Biomarkers

  • p70S6 kinase

  • Phosphatase and tensin homolog

  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

  • Phosphorylated 4E-binding protein 1

  • Promyelocytic Leukemia

  • Hypoxia-inducible factor-1

  • Insulin-like growth factor 1

  • Serine/threonine-protein kinase mTOR

Drug/Treatment

  • Ciclopirox

  • Ferrous sulfate

  • Rapacan

  • Mecasermin

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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