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4613 : SMYD3-mediated lysine methylation is critical for the activation of AKT1 in human cancer

Researchers

Presenter

  • Yuichiro Yoshioka

Principal Investigators

  • Yusuke Nakamura

  • Ryuji Hamamoto

Medical Centers

  • The University of Chicago Medical Center, Chicago, IL

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Thymomas

  • Solid malignancies

Biomarkers

  • AKT Serine

  • Phosphatase and tensin homolog

  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

  • Pyruvate

  • Pyruvate dehydrogenase kinase 1

  • Serine/threonine-protein kinase mTOR

  • Tensin 1

Drug/Treatment

  • Phosphatidylinositol

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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