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4605 : Metastasis-associated tumor cell phenotypes in TNBC is regulated by Wnt-beta-catenin pathway signals

Researchers

Presenter

  • Nandini Dey

Principal Investigators

  • Jennifer H. Carlson

  • Pradip De

  • Brian R. Leyland-Jones

Medical Centers

  • Avera Research Institute, Sioux Falls, SD.

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Triple-negative breast cancer

  • Brain metastasis

  • Breast cancer

  • Solid malignancies

Biomarkers

  • Adenomatous Polyposis Coli

  • beta-catenin

  • Phosphatase and tensin homolog

  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

  • Dishevelled segment polarity protein 1

Drug/Treatment

  • DE-074

  • Sulindac

  • XAV939

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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