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4453 : Molecular hallmarks of drug resistance to DNA methylation inhibitors and alternative therapeutic regimen for overcoming resistance

Researchers

Presenter

  • Khushboo Agrawal

Principal Investigators

  • Petr Vojta

  • Dusan Holub

  • Rastislav Slavkovsky

  • Ivo Frydrych

  • Petr Dzubak

  • Marcela Krecmerova

  • Marian Hajduch

Medical Centers

  • Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University and University Hospital, Olomouc, Czech Republic.

  • Institute of Organic Chemistry and Biochemistry of the CAS, Prague, Czech Republic

Locations

  • Czech Republic

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Solid malignancies

Biomarkers

  • p53

  • Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Theta

  • DNA methylation

Drug/Treatment

  • 5-Azacytidine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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