// App-Quantinova.ai

4370 : Genome-wide CRISPR-Cas9 screens reveal loss of redundancy between PKMYT1 and WEE1 in patient-derived glioblastoma stem-like cells

Researchers

Presenter

  • Chad Toledo

Principal Investigators

  • Ding Yu

  • Pia Hoellerbauer

  • Ryan Davis

  • Ryan Basom

  • Emily Girard

  • Philip Corrin

  • Hamid Bolouri

  • Jerry Davison

  • Qing Zhang

  • Do-Hyun Nam

  • Jeongwu Lee

  • Steven Pollard

  • Jeffery Delrow

  • Bruce Clurman

  • James Olson

  • Patrick Paddison

Medical Centers

  • Fred Hutchinson Cancer Resaerch Center, Seattle, WA

  • Lerner Research Institute, Cleveland Clinic, Cleveland, OH.

  • Edinburgh CRUK Cancer Research Centre and MRC Centre for Regenerative Medicine, The University of Edinburgh, Edinburgh, United Kingdom.

Locations

  • United States

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Glioblastoma

  • Brain cancer

  • Solid malignancies

  • Gliomas

Biomarkers

  • WEE1 G2 Checkpoint Kinase

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

Copyright © 2026. QuantiNova All rights reserved