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4310 : Regular intake of high-fat diet exacerbates oxidative stress-mediated DNA hypermethylation and activation of Nrf2-Keap1 signaling in UVB-induced skin tumors in SKH-1 hairless mice

Researchers

Presenter

  • Tripti Singh

Principal Investigators

  • Ram Prasad

  • Santosh K. Katiyar

Medical Centers

  • University of Alabama at Birmingham, Birmingham, AL

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

Disease

  • Solid malignancies

  • Heme oxygenase 1 deficiency

Biomarkers

  • Proto-oncogene tyrosine-protein kinase ROS

  • Heme oxygenase-1

  • Superoxide dismutase

  • DNA methylation

Drug/Treatment

  • Superoxide dismutase

  • glutathione

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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