// App-Quantinova.ai

4260 : 3D colorectal cancer organoids as preclinical models for assessment of activity of RAF inhibitor BGB-283

Researchers

Presenter

  • Xiaoran Wu

Principal Investigators

  • Chunyan Fu

  • Xi Yuan

  • Lianhai Zhang

  • Xiaohong Wang

  • Jiafu Ji

  • Lusong Luo

Medical Centers

  • BeiGene (Beijing) Co., Ltd., Beijing, China

  • Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Breast Oncology, Peking University Cancer Hospital & Institute, Beijing, China

Locations

  • China

Companies

  • BeiGene (Beijing) Co

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Melanoma

  • Colorectal Cancer

  • Solid malignancies

Biomarkers

  • Mitogen-activated protein kinase

  • B-Raf proto-oncogene, serine/threonine kinase

  • KRAS proto-oncogene, GTPase

Drug/Treatment

  • Vemurafenib

  • BGB-283

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A