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4153 : Abnormal expression of MUC1 mucin on colon epithelia stimulates production of pro-inflammatory cytokines promoting colitis-associated colon cancer in a murine model

Researchers

Presenter

  • Sandra Cascio

Principal Investigators

  • Jacque Faylo

  • Jia Xue

  • Olivera Finn

Medical Centers

  • University of Pittsburgh, School of Medicine, Pittsburgh, PA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Colorectal Cancer

  • Ulcerative colitis

  • Solid malignancies

Biomarkers

  • Kerbs von Lungren 6 antigen

  • Arginase 1

  • Enhancer of zeste homolog 2

  • Interleukin 10

  • Interleukin 6

Drug/Treatment

  • Sodium sulfate

  • Azoxymethane

  • Dex-HEMA

  • Interleukin-10

  • EZH2

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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