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4123 : Thymoquinone inhibits bone metastasis in a breast cancer mouse model by modulating CXCR4/CXCL12 signaling axis

Researchers

Presenter

  • Muthu K. Shanmugam

Principal Investigators

  • Annie Hsu

  • Kam Man Hui

  • Benny K.H. Tan

  • Gautam Sethi

Medical Centers

  • National University Hospital Singapore, Singapore, Singapore

  • National Cancer Centre Singapore, Singapore, Singapore

Locations

  • Singapore

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Bone metastases

  • Breast cancer

  • Bone Cancer

  • Solid malignancies

Biomarkers

  • Proliferation marker protein Ki-67

  • C-X-C motif chemokine receptor 4

  • Cyclooxygenase-2

  • Kinase Insert Domain Receptor

  • Stromal cell-derived factor 1

Drug/Treatment

  • thymoquinone

  • CXCL12

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A