// App-Quantinova.ai

3736 : Schlafen 11 (SLFN11) blocks RNA synthesis upon replicative damage, a novel mechanism for killing cancer cells in response to DNA damaging agents

Researchers

Presenter

  • Junko Murai

Principal Investigators

  • Sai-wen Tang

  • Yves Pommier

Medical Centers

  • National Institute of Health, Bethesda, MD

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Solid malignancies

Biomarkers

  • Cyclin dependent kinase 1

  • Cyclin dependent kinase 2

Drug/Treatment

  • camptothecin

  • Seliciclib

  • Doxorubicin

  • Irinotecan

  • Etoposide

  • Etoposide phosphate

  • Cisplatin

  • Topotecan Hydrochloride

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

Copyright © 2026. QuantiNova All rights reserved