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3715 : Benzimidazolone sulphonamides - potent, selective and drug-like inhibitors of poly(ADP Ribose) Glycohydrolase (PARG)

Researchers

Presenter

  • Allan Jordan

Principal Investigators

  • Ben Acton

  • Nicola Hamilton

  • James Hitchin

  • Colin Hutton

  • Dominic James

  • Cliff Jones

  • Stuart Jones

  • Alison McGonagle

  • Helen Small

  • Kate Smith

  • Alex Stowell

  • Julie Tucker

  • Ian Waddell

  • Bohdan Waszkowycz

  • Donald Ogilvie

Medical Centers

  • Cancer Research UK Manchester Institute, Manchester, United Kingdom

  • Astra Zeneca, Manchester, United Kingdom

  • Newcastle University, Newcastle upon Tyne, United Kingdom

Locations

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Solid malignancies

Biomarkers

  • Ataxia Telangiectasia And Rad3-Related Protein

  • Ataxia-telangiectasia mutated

Drug/Treatment

  • ribose

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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