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3706 : p53 represses pyrimidine catabolic gene dihydropyrimidine dehydrogenase (DPYD) expression following thymidylate synthase (TS) inhibition

Researchers

Presenter

  • Prashanth Ravishankar Gokare

Principal Investigators

  • Niklas Finnberg

  • Jenny Dai

  • Maureen Murphy

  • Wafik El-Deiry

Medical Centers

  • Fox Chase Cancer Center, Philadelphia, PA

  • Pennsylvania State University, Hershey, PA.

  • Wistar Institute, Philadelphia, PA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Solid malignancies

Biomarkers

  • N/A

Drug/Treatment

  • Adrucil injection

  • Methotrexate

  • Raltitrexed

Outcome

  • N/A

Study Design

  • Pharmacokinetics

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • N/A

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